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Histamine Intolerance Test
£295.00
The Histamine Intolerance Test identifies genetic and biochemical predispositions that may contribute to histamine intolerance, helping uncover root causes of symptoms.
Sample type: Finger-prick dry blood (home collection)
Turnaround time: 10 working days
The Histamine Intolerance Test provides valuable insight into how your body breaks down and regulates histamine — a compound involved in immune responses, digestion, and the nervous system. When histamine levels become imbalanced, it can trigger a wide range of symptoms, from headaches and skin reactions to digestive discomfort and allergy-like responses.
This test assesses genetic and biochemical predispositions that may contribute to histamine intolerance, helping uncover the underlying reasons why your body may struggle with histamine metabolism. By identifying these factors, the test provides guidance for personalised nutritional and lifestyle strategies aimed at restoring balance and reducing symptoms.
What the test measures:
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Histamine metabolism pathways – How efficiently your body breaks down histamine
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Genetic predispositions – Variants that may affect enzymes such as DAO and HNMT
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Biochemical balance – Insights into nutrient co-factors needed to support histamine clearance
- Order your preferred test
- Receive your kit via post with full collection instructions
- Collect your sample at home and return to lab using provided packaging
- Receive your results once they have been processed by the lab
- If you want an in-depth review of your results to understand the findings, book a Lab Test Results Consultation
- If you would like a personalised Nutrition & Lifestyle Action Plan based on your findings, book an Initial Consultation
- Need help choosing a test? Contact us, or book a free 15-minute Discovery Call with our team
This test is ideal for those experiencing symptoms that may indicate impaired histamine metabolism such as:
- Anxiety or mood instability
- Gastrointestinal disturbance (bloating, diarrhoea, nausea)
- Insomnia
- Migraines or headaches
- Respiratory symptoms mimicking allergies
- Unexplained skin reactions (flushing, hives, itching)
It is also appropriate for those who react adversely to histamine‑rich foods — such as alcohol, aged cheese, fermented products or teas — or to certain medications like NSAIDs, and those with a personal or family history of food intolerance, allergy or gastrointestinal disorders.
Frequently Asked Questions
Histamine intolerance usually occurs when there's an imbalance between histamine intake or production and the body’s ability to break it down. This may be due to gut dysfunction, enzyme deficiencies (like DAO or HNMT), genetic factors, or certain medications.
Unlike allergy tests that detect IgE-mediated reactions, this test looks at your body’s capacity to clear histamine. Histamine intolerance isn’t a true allergy — it’s more of a metabolic imbalance that leads to allergy-like symptoms without an identifiable allergen.
Yes. Histamine intolerance often causes symptoms that are inconsistent or triggered by specific foods, stress, alcohol, or hormone fluctuations. Testing can help uncover the underlying cause of these unexplained flare-ups.
What Our Customers Say
“I had allergy-like symptoms for years with no obvious cause. I now know I have histamine intolerance. This test explained so much I couldn’t recommend it more highly to anyone who is frustrated and looking for clear answers.”
– Roxanne H
“Game-changer for my skin and digestion. It sounds a bit silly but I had no idea certain foods I’ve eaten my whole life (seemingly without a problem) were making things worse until I took this test!”
– Stephanie G
“So helpful. The test results explained my symptoms and Carmen’s personalised health plan helped me start managing them.”
– Shash K
