Histamine Intolerance Test

£295.00

Histamine intolerance occurs when the body struggles to break histamine down efficiently, leading to a build-up that can cause a range of unpleasant symptoms.

Histamine is a natural compound with many essential roles in the body. It acts as a neurotransmitter, helping to send messages between the brain and nervous system. It also stimulates the release of stomach acid to aid digestion and forms part of the immune response, being released after stress, injury or allergic reactions. Histamine intolerance occurs when the body struggles to break histamine down efficiently, leading to a build-up that can cause a range of unpleasant symptoms.

  • Order your preferred test option (Essential or Comprehensive package)
  • Receive your kit via post with full collection instructions
  • Collect your sample and return to lab using provided packaging
  • Results and summary report sent via email — plus book your in-depth clinical review session if purchased.
  • Need Help Choosing a Test? Get in touch or book a free 15-minute discovery call with our team —
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This test is ideal for those experiencing symptoms that may indicate impaired histamine metabolism, including unexplained skin reactions (flushing, hives, itching), gastrointestinal disturbance (bloating, diarrhoea, nausea), frequent migraines or headaches of unknown origin, respiratory symptoms mimicking allergies, insomnia, anxiety or mood instability. It is also appropriate for those who react adversely to histamine‑rich foods—such as alcohol, aged cheese, fermented products or teas—or to certain medications like NSAIDs, and those with a personal or family history of food intolerance, allergy or gastrointestinal disorders.

Frequently Asked Questions

Histamine intolerance usually occurs when there's an imbalance between histamine intake or production and the body’s ability to break it down. This may be due to gut dysfunction, enzyme deficiencies (like DAO or HNMT), genetic factors, or certain medications.

Unlike allergy tests that detect IgE-mediated reactions, this test looks at your body’s capacity to clear histamine. Histamine intolerance isn’t a true allergy — it’s more of a metabolic imbalance that leads to allergy-like symptoms without an identifiable allergen.

Yes. Histamine intolerance often causes symptoms that are inconsistent or triggered by specific foods, stress, alcohol, or hormone fluctuations. Testing can help uncover the underlying cause of these unexplained flare-ups.

What Our Customers Say

“I had allergy-like symptoms for years with no obvious cause. I now know I have histamine intolerance. This test explained so much I couldn’t recommend it more highly to anyone who is frustrated and looking for clear answers.”

– Rosanne U

“Game-changer for my skin and digestion. It sounds a bit silly but I had no idea certain foods I’ve eaten my whole life (seemingly without a problem) were making things worse until I took this test!”

– Stephanie G

“So helpful. The results matched my symptoms exactly and gave me a clear plan for managing them naturally with the help of Carmen’s personalised plan.”

– Shash K